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Naslov Freeze-dried nanocrystal dispersion of novel deuterated pyrazoloquinolinone ligand (DK-I-56-1): Process parameters and lyoprotectant selection through the stability study (Article)
Autori Mitrovic Jelena R Bjelosevic-Ziberna Maja Vukadinovic Aleksandar A  Knutson Daniel E Sharmin Dishary Kremenovic Aleksandar S  Grabnar Pegi Ahlin Planinsekb Odon Lunter Dominique Jasmin Cook James M Savic Miroslav M  Savic Snezana D  
Info EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, (2023), vol. 189 br. , str. -
Projekat Science Fund of the Republic of Serbia [7749108]; National Institutes of Health, USA [R01 NS076517, R01 MH096463]; National Science Foundation, Division of Chemistry [CHE-1625735]
Ispravka Web of Science   Članak   Elečas   Rang časopisa  
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Naslov High amount of lecithin facilitates oral delivery of a poorly soluble pyrazoloquinolinone ligand formulated in lipid nanoparticles: Physicochemical, structural and pharmacokinetic performances (Article)
Autori Mitrovic Jelena R Divovic-Matovic Branka Knutson Daniel E Petkovic Milos R  Djorovic Djordje J  Randjelovic Danijela V  Dobricic Vladimir D  Djokovic Jelena B Lunter Dominique Jasmin Cook James M Savic Miroslav M  Savic Snezana D  
Info INTERNATIONAL JOURNAL OF PHARMACEUTICS, (2023), vol. 633 br. , str. -
Projekat Science Fund of the Republic of Serbia [7749108]; Ministry of Education, Science and Technological Development, Republic of Serbia [451-03-68/2022-14/200161]; NIH [R01NS076517, 451-03-68/2022-14/200026]; project Neuroimmune aspects of mood, anxiety and cognitive effects of leads/drug candidates acting at GABAA and/or sigma-2 receptors: In vitro/in vivo delineation by nano-and hiPSC-based platforms-NanoCellEmoCog; University of Belgrade - Institute of Chemistry, Technology and Metallurgy; [DA-043204]
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Naslov Behavioural interaction of pyrazoloquinolinone positive allosteric modulators at alpha 6GABA(A) receptors and diazepam in rats: Anti-diazepam-induced ataxia action as a structure-dependent feature (Article)
Autori Divovic-Matovic Branka Knutson Daniel E Mitrovic Jelena R Stevanovic Vladimir Stanojevic Boban R  Savic Snezana D  Cook James M Savic Miroslav M  
Info BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, (2022), vol. 131 br. 6, str. 514-524
Projekat Science Fund of the Republic Serbia [7749108]; Ministry of Education, Science and Technological Development, Republic of Serbia [451-03-68/2022-14/200161]; NIH [DA-043204, R01NS076517]
Ispravka Web of Science   Članak   Elečas   Rang časopisa   Citati: Web of Science  
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Naslov Positive modulation of alpha 5GABAA receptors leads to dichotomous effects in rats on memory pattern and GABRA5 expression in prefrontal cortex and hippocampus (Article)
Autori Santrac Anja Batinic Bojan A  Timic-Stamenic Tamara S Arandjelovic Jovana Sharmin Dishary Knutson Daniel E Cook James M Savic Miroslav M  
Info BEHAVIOURAL BRAIN RESEARCH, (2022), vol. 416 br. , str. -
Projekat Ministry of Education, Science and Technological Development, Republic of Serbia; University of Belgrade-Faculty of Pharmacy [451-03-9/2021-14/200161]; National Institutes of Health (NIH) - USA [DA-043
Ispravka Web of Science   Članak   Elečas   Rang časopisa   Citati: Web of Science  
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Naslov Overcoming the Low Oral Bioavailability of Deuterated Pyrazoloquinolinone Ligand DK-I-60-3 by Nanonization: A Knowledge-Based Approach (Article)
Autori Mitrovic Jelena R Divovic-Matovic Branka Knutson Daniel E Djokovic Jelena B Kremenovic Aleksandar S  Dobricic Vladimir D  Randjelovic Danijela V  Pantelic Ivana  Cook James M Savic Miroslav M  Savic Snezana D  
Info PHARMACEUTICS, (2021), vol. 13 br. 8, str. -
Projekat Ministry of Education, Science and Technological Development, Republic of Serbia [451-03-9/2021-14/200161, 451-03-09/2021-14/200126, 451-03-9/2021-14/200026]; National In
Ispravka Web of Science   Članak   Elečas   Rang časopisa   Citati: Web of Science   Scopus  
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Naslov Nanocrystal dispersion of DK-I-56-1, a poorly soluble pyrazoloquinolinone positive modulator of alpha 6 GABAA receptors: Formulation approach toward improved in vivo performance (Article)
Autori Mitrovic Jelena R Divovic Branka Knutson Daniel E Djokovic Jelena B Vulic Predrag J  Randjelovic Danijela V  Dobricic Vladimir D  Calija Bojan R  Cook James M Savic Miroslav M  Savic Snezana D  
Info EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, (2020), vol. 152 br. , str. -
Projekat Ministry of Education, Science and Technological Development of the Republic of Serbia [TR34031, OI175076]; National Institutes of Health (NIH) - USA [R01 NS076517, R01 M
Ispravka Web of Science   Članak   Elečas   Rang časopisa   Citati: Web of Science  
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Naslov Combatting the opioid and benzodiazepine epidemic by the synthesis of novel safer drugs designed to be functionally selective for alpha 5-or alpha 6-containing GABAA receptors (Meeting Abstract)
Autori Knutson Daniel E Li Guanguan Prevot Thomas Arnold Leggy Chiou Lih-Chu Ernst Margot Mihovilovic Marko Savic Miroslav M  Sieghart Werner Sibille Etienne Cook James M 
Info ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, (2019), vol. 258 br. , str. -
Ispravka Web of Science   Elečas   Citati: Web of Science  
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Naslov Nanosuspension formulation of DK-I-56-1, a deuterated ligand functionally selective for the alpha 6 GABAA receptors, induces hyperlocomotion in mice (Meeting Abstract)
Autori Divovic-Matovic Branka Mitrovic Jelena R Knutson Daniel E Batinic Bojan A  Savic Snezana D  Cook James M Savic Miroslav M  
Info EUROPEAN NEUROPSYCHOPHARMACOLOGY, (2019), vol. 29 br. , Suppl. 6, str. S327-S328
Ispravka Web of Science   Članak   Elečas   Rang časopisa   Citati: Web of Science  
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Naslov Treatment of sensorimotor gating deficits in neuropsychiatric disorders using deuterated alpha 6-GABAAR subtype selective ligands (Meeting Abstract)
Autori Knutson Daniel E Kodali Revathi Treven Marco Divovic Branka Lee Hsin-Jung Chou Jui-Feng Chen Hon-Lie Chiou Lih-Chu Ernst Margot Mihovilovic Marko Savic Miroslav M  Sieghart Werner Cook James M 
Info ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, (2019), vol. 257 br. , str. -
Ispravka Web of Science   Elečas   Citati: Web of Science  
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Naslov Trigeminal neuropathic pain development and maintenance in rats are suppressed by a positive modulator of alpha 6 GABA(A) receptors (Article)
Autori Vasovic Dina D Divovic Branka Treven Marco Knutson Daniel E Steudle Friederike Scholze Petra Obradovic Aleksandar Lj  Fabjan Jure Brkovic Bozidar B Sieghart Werner Ernst Margot Cook James M Savic Miroslav M  
Info EUROPEAN JOURNAL OF PAIN, (2019), vol. 23 br. 5, str. 973-984
Projekat Ministry of Education, Science and Technological Development, R. Serbia-Grant [175,076]; FWF [I2306]; National Institutes of Health [MH096463, NS076517]; Milwaukee Institute for Drug Discovery; University of Wisconsin-Milwaukee's Shimadzu Laboratory for A
Ispravka Web of Science   Članak   Elečas   Rang časopisa   Citati: Web of Science   Scopus  
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